Bioanalytical Services for Small Molecule Drug Development
Bioanalysis of small molecule drugs is crucial for understanding their pharmacodynamics (PD) and pharmacokinetics (PK), providing detailed insights into how these drugs affect gene and protein expression, which is essential for determining their efficacy, safety, and mechanism of action. Accurate bioanalysis supports the optimization of drug dosing, identification of biomarkers for therapeutic response, and compliance with regulatory standards, ultimately facilitating the development of effective and safe small molecule therapeutics
Our Expertise
While we do not typically analyze small molecules directly, we leverage advanced genomic and proteomic tools to study gene expression and protein expression. Our expertise in technologies such as qPCR, ddPCR, ELISA, MSD, and LC/MS/MS allows us to provide precise and insightful analysis of molecular responses to small molecule drugs. By focusing on gene and protein expression, we offer crucial insights into the pharmacodynamics (PD) of your drug candidates, supporting the successful advancement of your development programs.
Analytical Support Through All Stages of Product Lifecycle
Phase
Technologies
Application
Preclinical
qPCR, ddPCR, ELISA, MSD, Western Blot, LC/MS/MS
- In vitro efficacy studies
- Gene Expression Analysis
- Protein Expression Analysis
Clinical
qPCR, ddPCR, ELISA, MSD, LC/MS/MS
- Gene Expression Analysis
- Protein Expression Analysis
- Biomarker analysis