Ensure the Success of Your Biological Drug Development
Avance Provides Assays to Support your Biopharmaceutical Development & Manufacturing
Avance Biosciences™ is a world-leading CRO specializing in GLP & GMP compliant biological assay development, assay validation, and sample testing services in support of biological drug discovery, development and manufacturing.
What We Do:
We offer CGMP/GLP-compliant assay development, assay validation, and sample testing services to ensure strict regulatory compliance and a smooth journey to market.
Cell bank and viral seed characterization assays
- Microbial assays for bacterial cell bank release, including identity, purity, stability, viability, and phage contamination
- qPCR and ddPCR for plasmid copy number or inserted gene copy number
- Sanger sequencing for plasmid and inserted gene sequence verification
- Next-generation sequencing (NGS) for plasmid and viral genome confirmation
- Restriction mapping for plasmid evaluation
- Southern blots for integration site and inserted gene structure analysis
- NGS for phage ID
DNA sequencing and residual host cell DNA assays for product release
- Sanger sequencing for plasmid drug products and viral vaccines
- NGS for inverted terminal repeats (ITR), GC-rich, and other challenging constructs
- cDNA sequencing and qPCR for multi-valent RNA vaccines
- qPCR residual host cell DNA testing for protein drug products
CAR-T and other gene or cell therapy product release
- Replication competent lentivirus (RCL) and vector copy number (VCN) testing
- qPCR and ddPCR assays for integrated gene copy analysis
- NGS amplicon sequencing for product characterization
- Potency and infectivity assays
- Transfection assay via single-cell NGS
- Transfection assay via colony picking and Sanger sequencing
- STEMvision for colony-forming unit (CFU) assays
Who We Are:
We are a team of dedicated scientists, and quality control professionals focused on meeting your needs and completing your challenging drug development and manufacturing projects.
When you partner with Avance Biosciences™, we give you undivided attention, share our experience and knowledge, and respond to your needs in a timely manner. Contact our technical staff to discuss how we can support you in your project!
We look forward to meeting you at this year’s event!
If you need a specific assay to advance your drug development and/or manufacturing initiatives, please stop by our booth to discuss how we can help.
When you partner with Avance Biosciences™, you gain a CRO partner that is creative, collaborative and dedicated to sound science with a focus on the regulatory requirements our partners require. Contact our technical staff to discuss how we can support you in your project!
