STEMvision™ Colony-Forming Unit Services
The colony-forming unit (CFU) assay is considered the gold standard in vitro functional assay for identifying and enumerating hematopoietic progenitor cells. Specifically designed for CFU assays, the STEMvision™ platform automates the imaging, classification, and quantification of hematopoietic colonies derived from human or mouse progenitor cells. By providing accurate, consistent, and reproducible results, it proves to be an invaluable tool for laboratories engaged in hematopoietic stem cell research and related applications.
Our Expertise
We have integrated the STEMvision™ Platform into our suite of analytical tools to enhance our capability to support gene and cell therapy product characterization for regulatory submissions. Drawing on our experience, we assist clients in validating various CFU assays aimed at characterizing gene-edited therapeutic cells, including CD34+ cells.
Selected Application
Hematopoietic Stem and Progenitor Cell Analysis
CFU assays are essential for evaluating the clonogenicity and multipotent differentiation capabilities of hematopoietic stem and progenitor cells (HSPCs). These assays are crucial for assessing changes in progenitor cell frequency following HSPC expansion or genomic manipulation. The STEMvision™ platform facilitates the analysis of HSPCs from both human and mouse cultures, providing precise and reliable results.