Analytical Services for Vaccine Development

Analytical and bioanalytical methods are essential in vaccine development, ensuring safety, efficacy, and quality at every stage. These techniques offer vital insights into the product’s identity, purity, stability, potency, and safety. They are pivotal in assessing immune responses during both preclinical and clinical phases and in upholding strict quality control during manufacturing. By enabling precise characterization and evaluation, these methods facilitate the creation of vaccines that adhere to rigorous regulatory standards and effectively address global health challenges.

Our Expertise

Take advantage of our expertise in genomics, proteomics, and immunoassays and let Avance Biosciences support your vaccine development and manufacturing campaigns. We assist clients with all vaccine types, including mRNA vaccines. Explore our comprehensive service offerings, categorized into preclinical studies, clinical studies, and Chemistry, Manufacturing, and Controls (CMC). Our tailored analytical solutions are crafted to accelerate each stage of vaccine development, ensuring rigorous testing for safety, efficacy, and quality assurance.

Analytical Support Through All Stages of Product Lifecycle

Phase

Technologies

Applications

Development

qPCR, ddPCR, PCR, Flow Cytometry, ELISA, MSD, LC/MS/MS

Raw material testing (i.e., plasmid release testing)
Sequence confirmation
Product characterization

Preclinical Studies

Cell-Based Assays, qPCR, ddPCR, PCR, Flow Cytometry, ELISA, MSD, LC/MS/MS

Immunogenicity studies
Cytokine profiling
PK/PD studies
Biodistribution studies

Clinical Studies

qPCR, ddPCR, PCR, Flow Cytometry, ELISA, MSD, LC/MS/MS

Immunogenicity Testing
Biomarker Analysis
PK/PD studies
Patient stratification
Cytokine profiling

CMC Support

qPCR, ddPCR, PCR, Flow Cytometry, ELISA, MSD, LC/MS/MS

Identity assays
Characterization assays
Batch consistency testing
Host cell proteins
Host cell residual DNA
Potency assays
Stability studies
Compendial methods
Adventitious agent testing

Have Questions?

Partner with us for comprehensive analytical support to advance your vaccine development efforts. To learn more about our services or to discuss your project needs, please contact us.